Methods and apparatus to configure virtual private mobile networks for security are disclosed. A disclosed example method includes identifying, in a wireless network, a communication from a user equipment that matches a security event profile, transmitting, from the wireless network, an instruction to enable the user equipment to be communicatively coupled to a virtual private mobile network, the virtual private mobile network being provisioned for security within the wireless network, and enabling the user equipment to transmit a second communication through the virtual private mobile network securely isolated from other portions of the wireless network.