The disclosure provides a method and a base station for adjusting an uplink grant physical downlink control channel of a UE adaptively. The method includes: receiving a physical uplink shared channel transmitted on an uplink resource indicated by a current uplink grant physical downlink control channel from the UE; judging whether or not the UE has received the uplink grant physical downlink control channel successfully in accordance with the received physical uplink shared channel; and determining the number of control channel elements CCEs occupied by the uplink grant physical downlink control channel and/or a transmission power of the uplink grant physical downlink control channel in accordance with the judgment result.