Invention Grant
- Patent Title: Substituted morphinans and the use thereof
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Application No.: US14576718Application Date: 2014-12-19
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Publication No.: US09388162B2Publication Date: 2016-07-12
- Inventor: Andrew Kassick , Jeffrey Lockman , Laykea Tafesse
- Applicant: Purdue Pharma L.P.
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: C07D401/06
- IPC: C07D401/06 ; C07D215/20 ; C07D215/14 ; C07D471/08

Abstract:
The application is directed to compounds of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4a, and R4b are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
Public/Granted literature
- US20150175571A1 Substituted Morphinans and the Use Thereof Public/Granted day:2015-06-25
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