Invention Grant
- Patent Title: Intermediate of Ertapenem, a composition comprising the same and preparation methods thereof
- Patent Title (中): 呃替培南的中间体，其组合物及其制备方法
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Application No.: US13266947Application Date: 2010-04-30
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Publication No.: US09388184B2Publication Date: 2016-07-12
- Inventor: Ying Shi , Kun Li , Zan Xie , Xuebin Zhao , Jian Lv , Xiuqin Yu
- Applicant: Ying Shi , Kun Li , Zan Xie , Xuebin Zhao , Jian Lv , Xiuqin Yu
- Applicant Address: CN Hebei
- Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
- Current Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
- Current Assignee Address: CN Hebei
- Agency: Cantor Colburn LLP
- Priority: CN200910136995 20090430
- International Application: PCT/CN2010/000607 WO 20100430
- International Announcement: WO2010/124531 WO 20101104
- Main IPC: C07D477/20
- IPC: C07D477/20
Abstract:
Intermediates of Ertapenem of formula 2a wherein Np represents (I) or (II), and P1 and P2 represent carboxyl protecting groups, and their preparation methods. Compound 2a prepared by the present methods in solid form is amorphous. The present invention also relates to a composition comprising at least 95% of the intermediate of Ertapenem of formula 2a.
Public/Granted literature
- US20120095209A1 INTERMEDIATE OF ERTAPENEM, A COMPOSITION COMPRISING THE SAME AND PREPARATION METHODS THEREOF Public/Granted day:2012-04-19
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