Invention Grant
- Patent Title: Immunoconjugates with an intracellularly-cleavable linkage
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Application No.: US13921747Application Date: 2013-06-19
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Publication No.: US09388237B2Publication Date: 2016-07-12
- Inventor: Serengulam V. Govindan
- Applicant: Immunomedics, Inc.
- Applicant Address: US NJ Morris Plains
- Assignee: Immunomedics, Inc.
- Current Assignee: Immunomedics, Inc.
- Current Assignee Address: US NJ Morris Plains
- Agent Richard A. Nakashima
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/28 ; A61K47/48 ; C07K16/18 ; A61K45/06 ; C07K16/30
Abstract:
The invention relates to therapeutic conjugates with improved ability to target various cancer cells containing a targeting moiety and a therapeutic moiety. The targeting and therapeutic moieties are linked via an acid cleavable linkage that increases therapeutic efficacy of the immunoconjugate.
Public/Granted literature
- US20140004078A1 Immunoconjugates with an Intracellularly-Cleavable Linkage Public/Granted day:2014-01-02
Information query
