A thermal frame for an opening in a refrigerated enclosure includes a perimeter frame segment fixed to the refrigerated enclosure along a perimeter of the opening. The thermal frame includes a first vacuum panel fixed relative to the perimeter frame segment and configured to reduce heat transfer through the perimeter frame segment. The thermal frame may include a mullion frame segment fixed to the refrigerated enclosure and dividing the opening into a plurality of smaller openings. The thermal frame may include a second vacuum panel fixed relative to the mullion frame segment and configured to reduce heat transfer through the mullion frame segment.