Invention Grant
- Patent Title: Polymorph compositions, methods of making, and uses thereof
- Patent Title (中): 多晶型组合物,制备方法及其应用
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Application No.: US13800480Application Date: 2013-03-13
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Publication No.: US09399019B2Publication Date: 2016-07-26
- Inventor: R. Loch Macdonald , Cara R. Davis , Kevin Burton , Gary Winchester , Angela R. Stella , Parissa Heshmati
- Applicant: Edge Therapeutics, Inc. , Evonik Corporation
- Applicant Address: US NY Parsippany US NJ Berkeley Heights
- Assignee: Evonik Corporation,Edge Therapeutics, Inc.
- Current Assignee: Evonik Corporation,Edge Therapeutics, Inc.
- Current Assignee Address: US NY Parsippany US NJ Berkeley Heights
- Agency: Chiesa Shahinian & Giantomasi PC
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/16 ; A61K31/4418 ; A61K31/4422

Abstract:
The described invention provides a biodegradable, biocompatible delivery system of flowable sustained release microparticulate composition of a substantially pure crystalline form of a bioactive agent such as, for example, nimodipine, a process of preparing a therapeutic form of a substantially pure crystalline form of the bioactive agent and a method for treating an interruption of a cerebral artery in a subarachnoid space at risk of interruption caused by brain injury in a mammal, which reduces signs or symptoms of at least one delayed complication associated with brain injury.
Public/Granted literature
- US20130302431A1 Polymorph Compositions, Methods of Making, and Uses Thereof Public/Granted day:2013-11-14
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