Invention Grant
US09399020B2 Hydrophilic matrix beadlet compositions with enhanced bioavailability
有权
具有增强的生物利用度的亲水基质珠粒组合物
- Patent Title: Hydrophilic matrix beadlet compositions with enhanced bioavailability
- Patent Title (中): 具有增强的生物利用度的亲水基质珠粒组合物
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Application No.: US14487400Application Date: 2014-09-16
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Publication No.: US09399020B2Publication Date: 2016-07-26
- Inventor: Jayant Deshpande , Subhrangsu Sengupta , Pravin Nalawade , Swapnil Khamborkar
- Applicant: OmniActive Health Technologies Limited
- Applicant Address: IN Mumbai
- Assignee: OmniActive Health Technologies Limited
- Current Assignee: OmniActive Health Technologies Limited
- Current Assignee Address: IN Mumbai
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: IN1660/MUM/2014 20140516; WOPCT/IB2014/001734 20140904
- Main IPC: A61K9/50
- IPC: A61K9/50 ; A61K9/14 ; A61K31/047 ; A23L1/00 ; A23L1/30 ; A23L1/302

Abstract:
The instant invention provides hydrophilic matrix beadlet compositions that include at least one fat soluble nutrient and an effective amount of cellulose polymer with low viscosity. The invention also provides a process for the preparation of the hydrophilic matrix composition by employing a fluid bed system or extrusion spheronization technique. This hydrophilic matrix beadlet composition is comprised of at least 5% to about 25% carotenoid wherein free lutein is present in combination with zeaxanthin. The free flowing nature of the composition allows it to be compressed into tablets or to be filled into two piece capsules or blended as a dry premix for beverage applications. These hydrophilic matrix compositions exhibit desired dissolution characteristics and at least 1.6 times more bioavailability as compared with marketed reference formulations containing modified starch, thus making it advantageous for nutraceutical applications.
Public/Granted literature
- US20150328158A1 HYDROPHILIC MATRIX BEADLET COMPOSITIONS WITH ENHANCED BIOAVAILABILITY Public/Granted day:2015-11-19
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