Invention Grant
- Patent Title: PVRL4 (Nectin4) is a receptor for measles virus
- Patent Title (中): PVRL4（Nectin4）是麻疹病毒的受体
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Application No.: US13980392Application Date: 2012-01-17
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Publication No.: US09399062B2Publication Date: 2016-07-26
- Inventor: Christopher D. Richardson
- Applicant: Christopher D. Richardson
- Applicant Address: CA Halifax, Nova Scotia
- Assignee: Christopher D. Richardson
- Current Assignee: Christopher D. Richardson
- Current Assignee Address: CA Halifax, Nova Scotia
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/IB2012/000183 WO 20120117
- International Announcement: WO2012/098465 WO 20120726
- Main IPC: A61K39/165
- IPC: A61K39/165 ; A01N63/00 ; C12N7/00 ; A61K39/42 ; A61K31/713 ; A61K35/76 ; G01N33/574 ; A61K35/768 ; C12Q1/68
Abstract:
PVRL4 is a tumor marker that is highly expressed on the surfaces of many carcinomas. Disclosed herein are compositions and methods that provide impetus for using measles virus as an oncolytic agent against PVRL4+ carcinomas and use of PVRL4-binding agents to interfere with viral infection.
Public/Granted literature
- US20130295114A1 PVRL4 (Nectin4) is a Receptor for Measles Virus Public/Granted day:2013-11-07
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