Invention Grant
US09399627B2 Substituted macrocyclic compounds having proteasome inhibitory activity
有权
具有蛋白酶体抑制活性的取代大环化合物
- Patent Title: Substituted macrocyclic compounds having proteasome inhibitory activity
- Patent Title (中): 具有蛋白酶体抑制活性的取代大环化合物
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Application No.: US14408140Application Date: 2013-06-14
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Publication No.: US09399627B2Publication Date: 2016-07-26
- Inventor: Michael C. Pirrung
- Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Gavrilovich, Dodd & Lindsey LLP
- Agent Joseph R. Baker, Jr.
- International Application: PCT/US2013/045854 WO 20130614
- International Announcement: WO2013/188750 WO 20131219
- Main IPC: C07D245/02
- IPC: C07D245/02 ; A61K31/395 ; C07D403/12 ; A61K45/06
Abstract:
The disclosure provides for novel compounds which have proteasome inhibitory activity, pharmaceutical compositions made thereof, and methods of use thereof to treat various disorders, including cancer and nonmalignant tumors.
Public/Granted literature
- US20150141392A1 SUBSTITUTED MACROCYCLIC COMPOUNDS HAVING PROTEASOME INHIBITORY ACTIVITY Public/Granted day:2015-05-21
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