Invention Grant
- Patent Title: Synthetic route to pactamycin and pactamycin analogs
- Patent Title (中): 合成途径到培养基和培美霉素类似物
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Application No.: US14758110Application Date: 2014-01-23
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Publication No.: US09399652B2Publication Date: 2016-07-26
- Inventor: Jeffrey Johnson , Justin Malinowski , Robert Sharpe
- Applicant: The University of North Carolina at Chapel Hill
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Myers Bigel & Sibley, P.A.
- International Application: PCT/US2014/012685 WO 20140123
- International Announcement: WO2014/116792 WO 20140731
- Main IPC: C07F7/10
- IPC: C07F7/10 ; C07F7/18 ; C07C275/24 ; C07C275/26
Abstract:
Methods and intermediates useful for making compounds of Formula (I) are described, including a general method of making an alpha, beta-diamino ketone by reacting an imine with a 2-amino-substituted 1,3-dicarbonyl in a Mannich addition reaction to produce said alpha,beta-diamino ketone.
Public/Granted literature
- US20150329570A1 SYNTHETIC ROUTE TO PACTAMYCIN AND PACTAMYCIN ANALOGS Public/Granted day:2015-11-19
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