Invention Grant
- Patent Title: Modulation of transthyretin expression
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Application No.: US14717746Application Date: 2015-05-20
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Publication No.: US09399774B2Publication Date: 2016-07-26
- Inventor: Brett P. Monia , Susan M. Freier , Andrew M. Siwkowski , Shuling Guo
- Applicant: Ionis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/113 ; A61K31/712
Abstract:
Provided herein are methods, compounds, and compositions for reducing expression of transthyretin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate transthyretin amyloidosis, or a symptom thereof.
Public/Granted literature
- US20150252367A1 MODULATION OF TRANSTHYRETIN EXPRESSION Public/Granted day:2015-09-10
Information query
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