A nickel—chromium—molybdenum—copper alloy resistant to 70% sulfuric acid at 93° C. and 50% sodium hydroxide at 121° C. for acid and alkali neutralization in the field of waste management; the alloy contains, in weight percent, 27 to 33 chromium, 4.9 to 7.8 molybdenum, 3.1 to 6.0 wt. % copper (when chromium is between 30 and 33 wt. %) or 4.7 to 6.0 wt. % copper (when chromium is between 27 and 29.9 wt. %), up to 3.0 iron, 0.3 to 1.0 manganese, 0.1 to 0.5 aluminum, 0.1 to 0.8 silicon, 0.01 to 0.11 carbon, up to 0.13 nitrogen, up to 0.05 magnesium, up to 0.05 rare earth elements, with a balance of nickel and impurities. Titanium or another MC carbide former can be added to enhance thermal stability of the alloy.