Invention Grant
- Patent Title: Method for detecting nucleosomes containing histone variants
- Patent Title (中): 检测含有组蛋白变体的核小体的方法
-
Application No.: US14239779Application Date: 2012-08-31
-
Publication No.: US09400276B2Publication Date: 2016-07-26
- Inventor: Jacob Vincent Micallef
- Applicant: Jacob Vincent Micallef
- Applicant Address: SG Singapore
- Assignee: SINGAPORE VOLITION PTE. LIMITED
- Current Assignee: SINGAPORE VOLITION PTE. LIMITED
- Current Assignee Address: SG Singapore
- Agency: Foley & Lardner LLP
- Priority: GB1115098.4 20110901
- International Application: PCT/GB2012/052131 WO 20120831
- International Announcement: WO2013/030579 WO 20130307
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/574 ; G01N33/68
Abstract:
The invention relates to a method for detecting and measuring the presence of mono-nucleosomes and oligo-nucleosomes and nucleosomes that contain particular histone variants and the use of such measurements for the detection and diagnosis of disease. The invention also relates to a method of identifying histone variant biomarkers for the detection and diagnosis of disease and to biomarkers identified by said method.
Public/Granted literature
- US20140206014A1 METHOD FOR DETECTING NUCLEOSOMES CONTAINING HISTONE VARIANTS Public/Granted day:2014-07-24
Information query
IPC分类:
