In an embodiment, a processor includes an issue circuit configured to issue instruction operations for execution. The issue circuit may be configured to monitor the source operands of the instruction operations, and to issue instruction operations for which the source operands (including predicate operands, as appropriate) are resolved. Additionally, the issue circuit may be configured to detect a null predicate that indicates that none of the vector elements will be modified by a corresponding instruction operation. The issue circuit may be configured to issue the corresponding instruction operation with the null predicate even if other source operands are not yet resolved.