Methods and system for optimizing an execution of a business process are disclosed. In one aspect, a request to execute a business process is received. The business process is executed on multiple threads, which may include multiple computations. The business process is optimized by determining an optimal number of threads for executing the business process by a thread optimization model. From the determined optimal number of threads, the computations in the threads may be distributed or reallocated iteratively by executing an inter-thread computations optimization model. Executing the thread optimization model and the inter-thread computations optimization model optimizes the execution of the business process.