Invention Grant
- Patent Title: Fatty acid treatment for cardiac patients
- Patent Title (中): 心脏病患者的脂肪酸治疗
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Application No.: US14523810Application Date: 2014-10-24
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Publication No.: US09402822B2Publication Date: 2016-08-02
- Inventor: Charles R. Roe
- Applicant: Baylor Research Institute
- Applicant Address: US TX Dallas
- Assignee: Baylor Research Institute
- Current Assignee: Baylor Research Institute
- Current Assignee Address: US TX Dallas
- Agency: Cooley LLP
- Main IPC: A61K31/194
- IPC: A61K31/194 ; A61K31/19 ; A61K31/20 ; A61K31/23

Abstract:
A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial β-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
Public/Granted literature
- US20150105585A1 FATTY ACID TREATMENT FOR CARDIAC PATIENTS Public/Granted day:2015-04-16
Information query
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