Invention Grant
- Patent Title: Neuronal pain pathway modulators
- Patent Title (中): 神经元疼痛途径调节剂
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Application No.: US14500745Application Date: 2014-09-29
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Publication No.: US09402826B2Publication Date: 2016-08-02
- Inventor: Richard Ambron , Ying-Ju Sung , Jeremy Greenwood , Leah Frye , Shi-Xian Deng , Yuli Xie , Donald W. Landry
- Applicant: The Trustees of Columbia University in the City of New York
- Applicant Address: US NY New York
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Baker Botts L.L.P
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/335 ; A61K31/235

Abstract:
The present invention relates to compounds that may be used to inhibit activation of protein kinase G (“PKG”). It is based, at least in part, on the discovery of the tertiary structure of PKG and the identification of molecules that either bind to the active site of PKG and/or are analogs of balanol.
Public/Granted literature
- US20150126576A1 NEURONAL PAIN PATHWAY MODULATORS Public/Granted day:2015-05-07
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