Invention Grant
- Patent Title: Compositions and methods of using chondroitinase ABCI mutants
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Application No.: US14480486Application Date: 2014-09-08
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Publication No.: US09402886B2Publication Date: 2016-08-02
- Inventor: Anthony O. Caggiano , Jennifer Iaci , Andrea Vecchione , Elizabeth Hunter
- Applicant: ACORDA THERAPEUTICS, INC.
- Applicant Address: US NY Ardsley
- Assignee: Acorda Therapeutics, Inc.
- Current Assignee: Acorda Therapeutics, Inc.
- Current Assignee Address: US NY Ardsley
- Agency: Pepper Hamilton LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/47 ; A61K38/46 ; C12N9/88 ; C12N9/26 ; C12N9/24 ; C12N9/14 ; C07H21/04 ; C07K1/00 ; A61K38/51
Abstract:
One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
Public/Granted literature
- US20150190483A1 COMPOSITIONS AND METHODS OF USING CHONDROITINASE ABCI MUTANTS Public/Granted day:2015-07-09
Information query
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