Invention Grant
- Patent Title: Inactivated poliovaccine
- Patent Title (中): 灭活的脊髓灰质炎疫苗
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Application No.: US13977399Application Date: 2011-12-29
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Publication No.: US09402892B2Publication Date: 2016-08-02
- Inventor: Andrew MacAdam
- Applicant: Andrew MacAdam
- Applicant Address: GB London
- Assignee: The Secretary of State for Health
- Current Assignee: The Secretary of State for Health
- Current Assignee Address: GB London
- Agency: Christensen O'Connor Johnson Kindness PLLC
- Priority: GB1022077.0 20101229
- International Application: PCT/GB2011/001779 WO 20111229
- International Announcement: WO2012/090000 WO 20120705
- Main IPC: C07K14/105
- IPC: C07K14/105 ; C07K14/085 ; A61K39/13 ; A61K39/125 ; C12N15/43 ; C12N15/41 ; C12N7/00 ; A61K39/12 ; A61K39/00
Abstract:
The invention provides an attenuated polio virus having a 5′ non-coding region consisting of the 5′ non-coding region of Sabin 3, modified so that it does not have a base pair mismatch in stem (a) or (b) of domain V, wherein seven or eight of the base pairs in stems (a) and (b) are U-A or A-U base pairs; and a capsid protein from the Sabin 1, Mahoney, MEF or Saukett strain.
Public/Granted literature
- US20130344108A1 INACTIVATED POLIOVACCINE Public/Granted day:2013-12-26
Information query
