Invention Grant
- Patent Title: Stabilized formulations containing anti-Ang2 antibodies
- Patent Title (中): 含有抗Ang2抗体的稳定制剂
-
Application No.: US13746669Application Date: 2013-01-22
-
Publication No.: US09402898B2Publication Date: 2016-08-02
- Inventor: Scott M. Walsh , Daniel B. Dix
- Applicant: Scott M. Walsh , Daniel B. Dix
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Alston & Bird LLP
- Agent Aparna G. Patankar
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61J1/06 ; A61J1/10 ; B65D85/00 ; A61K47/26 ; C07K16/22 ; A61K9/00 ; A61K47/18
Abstract:
The present invention provides pharmaceutical formulations comprising an antibody that specifically binds to angiopoietin 2 (Ang-2). The formulations may contain, in addition to an anti-Ang-2 antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months and after being subjected to thermal and other physical stress.
Public/Granted literature
- US20130186797A1 Stabilized Formulations Containing Anti-Ang2 Antibodies Public/Granted day:2013-07-25
Information query
