Invention Grant
- Patent Title: Antibiotic conjugates directly linked with steroid drugs
- Patent Title (中): 与类固醇药物直接连接的抗生素结合物
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Application No.: US14198939Application Date: 2014-03-06
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Publication No.: US09402912B2Publication Date: 2016-08-02
- Inventor: Santosh C. Sinha , Ken Chow , Liming Wang , Michael E. Garst , Mayssa Attar , Brandon D. Swift
- Applicant: Allergan, Inc.
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Barbara C. Potts
- Main IPC: C07D405/12
- IPC: C07D405/12 ; A61K47/48 ; A61K9/00 ; C07D215/56 ; C07D401/04 ; C07D471/04 ; C07D498/06
Abstract:
The present invention describes novel single drug entities, formed by direct linkage of an antibiotic to a steroidal drug. Upon topical application to the eye, the conjugate would undergo enzymatic and/or hydrolytic cleavage to release the individual drugs. The antibiotic is coupled directly to the steroid drug.
Public/Granted literature
- US20140256612A1 ANTIBIOTIC CONJUGATES DIRECTLY LINKED WITH STEROID DRUGS Public/Granted day:2014-09-11
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