Invention Grant
- Patent Title: Cyclosporine A steroid conjugates
- Patent Title (中): 环孢菌素A类固醇共轭物
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Application No.: US14199432Application Date: 2014-03-06
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Publication No.: US09402913B2Publication Date: 2016-08-02
- Inventor: Santosh C. Sinha , Ken Chow , Liming Wang , Michael E. Garst , Mayssa Attar , Brandon D. Swift
- Applicant: Allergan, Inc.
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Barbara C. Potts
- Main IPC: A61K38/12
- IPC: A61K38/12 ; C07K7/64 ; A61K47/48 ; A61K9/00

Abstract:
The present invention describes Cyclosporine A/steroid hybrid analogs. These single drug entities are formed by connecting a steroid with Cyclosporine A. Upon topical application to the eye, the conjugate hybrid would undergo enzymatic and/or hydrolytic cleavage to release the individual drugs.
Public/Granted literature
- US20140256651A1 Cyclosporine A steroid conjugates Public/Granted day:2014-09-11
Information query
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