Invention Grant
- Patent Title: Swallowable capsule and method for stimulating incretin production within the intestinal tract
-
Application No.: US14599350Application Date: 2015-01-16
-
Publication No.: US09403002B2Publication Date: 2016-08-02
- Inventor: Mir A. Imran , Mir Hashim , Emily Arnsdorf
- Applicant: InCube Labs, LLC
- Applicant Address: US CA San Jose
- Assignee: Rani Therapeutics, LLC
- Current Assignee: Rani Therapeutics, LLC
- Current Assignee Address: US CA San Jose
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61N1/36
- IPC: A61N1/36 ; A61K38/26 ; A61N1/05 ; A61N1/372 ; A61N1/06

Abstract:
Embodiments of the invention provide apparatus and methods for stimulating L cells in the intestinal tract to produce incretins for the treatment of conditions including diabetes and obesity. Many embodiments provide a method and apparatus for the treatment of diabetes by electrically stimulating L-cells to secrete incretins to stimulate or otherwise modulate the production of insulin. Particular embodiments provide a swallowable capsule for stimulating L-cells in the intestinal tract as the capsule moves through the tract. The capsule can include two or more electrodes for providing electrical stimulation to L-cells, a power source for powering one or more components of the capsule, a sensor for sensing the location of the capsule in the intestinal tract; a controller and a waveform generator for generating the electrical signals emitted by the electrodes to stimulate the L-cells to secrete incretins such as GLP-1 to stimulate insulin production for glucose regulation of diabetic conditions.
Public/Granted literature
- US20150174400A1 SWALLOWABLE CAPSULE AND METHOD FOR STIMULATING INCRETIN PRODUCTION WITHIN THE INTESTINAL TRACT Public/Granted day:2015-06-25
Information query