A mechano-chemical reactor comprising, driving means extended along one or more parallel axis, a mass made oscillating by the driving means along the direction of a vertical axis and an elastic system for a partial compensation of the inertial forces generated by the oscillating mass. The oscillating mass includes at least one restricted environment loaded with solid and/or liquid substances are loaded in order to be treated by the kinetic energy of milling bodies. The elastic system comprises flexible elements made of a titanium alloy which are either one-dimensional, i.e. a plurality of rectilinear parallel rods, or bi-dimensional, i.e. at least a polygonal plate having two sides parallel to the axis of the driving means. In rest conditions the flexible elements are extended substantially perpendicular to the direction of the oscillations of the mass.