A unit for sequencing and guiding items, in which the items are grouped into batches of one or more items; the unit comprises a first conveyor for advancing the items from an input station to an output station, and a sequencing apparatus cooperable with the items to form the batches and to drive them to the output station; the sequencing apparatus comprises a second conveyor comprising a track and plural movable elements independently moved along the track; the track has a work portion parallel to the first conveyor, and the movable elements include respective interacting portions, adapted to protrude over the first conveyor when the movable elements are advanced along the work portion of the track, and cooperating with the items to drive them to the desired positions along the first conveyor to define the batches and to locate the batches at the desired distances from one another.