Invention Grant
- Patent Title: Methods of using pyruvate kinase activators
- Patent Title (中): 使用丙酮酸激酶激活剂的方法
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Application No.: US14115293Application Date: 2012-05-03
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Publication No.: US09403792B2Publication Date: 2016-08-02
- Inventor: Shin-San M. Su
- Applicant: Shin-San M. Su
- Applicant Address: US MA Cambridge
- Assignee: AGIOS PHARMACEUTICALS, INC
- Current Assignee: AGIOS PHARMACEUTICALS, INC
- Current Assignee Address: US MA Cambridge
- Agency: Lando & Anastasi, LLP
- International Application: PCT/US2012/036411 WO 20120503
- International Announcement: WO2012/151450 WO 20121108
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D471/04 ; C07D319/18 ; A61K31/4704 ; A61K31/495 ; A61K31/496 ; A61K31/5025 ; A61K31/551 ; A61K31/635 ; A01N1/02
Abstract:
Described herein are compounds that activate pyruvate kinase, for use in a method for increasing lifetime of the red blood cells, for regulating 2,3-diphosphoglycerate levels in blood and for treating sickle cell anemia.
Public/Granted literature
- US20140148444A1 METHODS OF USING PYRUVATE KINASE ACTIVATORS Public/Granted day:2014-05-29
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