Invention Grant
- Patent Title: Indole-3-carboxamides as kinase inhibitors
- Patent Title (中): 吲哚-3-甲酰胺作为激酶抑制剂
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Application No.: US14510072Application Date: 2014-10-08
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Publication No.: US09403803B2Publication Date: 2016-08-02
- Inventor: Sougato Boral , Thomas C. Malone , Shimiao Wang
- Applicant: Allergan, Inc.
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Jonathan Bass
- Main IPC: C07D405/12
- IPC: C07D405/12 ; C07D209/42

Abstract:
This invention is directed to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and X are as defined herein. The compounds of Formula I are useful as receptor tyrosine kinase (RTK) inhibitors and can be used to treat such diseases as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders and metabolic diseases.
Public/Granted literature
- US20160102077A1 Indole-3-Carboxamides as Kinase Inhibitors Public/Granted day:2016-04-14
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