Invention Grant
- Patent Title: Mineralocorticoid receptor antagonists
- Patent Title (中): 盐皮质激素受体拮抗剂
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Application No.: US14557980Application Date: 2014-12-02
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Publication No.: US09403807B2Publication Date: 2016-08-02
- Inventor: Alejandro Crespo , Ping Lan , Rudrajit Mal , Anthony Ogawa , Hong Shen , Peter J. Sinclair , Zhongxiang Sun , Ellen K. Vande Bunte , Zhicai Wu , Kun Liu , Robert J. DeVita , Dong-Ming Shen , Min Shu , John Qiang Tan , Changhe Qi , Yuguang Wang , Richard Beresis
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia A. Shatynski; Anna L. Cocuzzo
- Main IPC: C07D413/06
- IPC: C07D413/06 ; C07D231/56 ; A61K31/404 ; A61K31/416 ; C07D403/06 ; C07D209/08 ; C07D209/10 ; A61K31/405 ; A61K31/4196 ; A61K31/722 ; A61K31/4245 ; A61K45/06 ; C07D403/04 ; C07D405/06 ; A61K31/4045 ; A61K31/422
Abstract:
The present invention is directed to compounds of the Formula I as well as pharmaceutically acceptable salts thereof, that are useful for treating aldosterone-mediated diseases. The invention furthermore relates to processes for preparing compounds of the Formula I, to their use for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of the Formula I.
Public/Granted literature
- US20150284376A1 MINERALOCORTICOID RECEPTOR ANTAGONISTS Public/Granted day:2015-10-08
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