Invention Grant
US09403824B2 Pyridonemorphinan analogs and biological activity on opioid receptors
有权
吡啶并吗啡类似物和对阿片受体的生物活性
- Patent Title: Pyridonemorphinan analogs and biological activity on opioid receptors
- Patent Title (中): 吡啶并吗啡类似物和对阿片受体的生物活性
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Application No.: US14607805Application Date: 2015-01-28
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Publication No.: US09403824B2Publication Date: 2016-08-02
- Inventor: Jeffrey Lockman , Laykea Tafesse , Mark A. Youngman
- Applicant: Purdue Pharma L.P.
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Sterne, Kessler, Goldstein & Fox, P.L.L.C.
- Main IPC: C07D471/08
- IPC: C07D471/08 ; C07D471/18 ; C07D471/22 ; C07D519/00
Abstract:
The application is directed to compounds of Formula I-A and pharmaceutically acceptable salts and solvates thereof, wherein , R1a-R3a, R4, Y and Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I-A to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
Public/Granted literature
- US20150203494A1 PYRIDONEMORPHINAN ANALOGS AND BIOLOGICAL ACTIVITY ON OPIOID RECEPTORS Public/Granted day:2015-07-23
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