Invention Grant
![Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use](/docs/US/2016-08-02/US09403832B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use
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Application No.: US14483898Application Date: 2014-09-11
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Publication No.: US09403832B2Publication Date: 2016-08-02
- Inventor: Yingzhi Bi , Kenneth Gordon Carson , Giovanni Cianchetta , Michael Alan Green , Godwin Kumi , Alan Main , Yulian Zhang , Glenn Gregory Zipp
- Applicant: Lexicon Pharmaceuticals, Inc.
- Applicant Address: US TX The Woodlands
- Assignee: Lexicon Pharmaceuticals, Inc.
- Current Assignee: Lexicon Pharmaceuticals, Inc.
- Current Assignee Address: US TX The Woodlands
- Agent Max Bachrach
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; C07B59/00
![Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use](/abs-image/US/2016/08/02/US09403832B2/abs.jpg.150x150.jpg)
Abstract:
Pyrazolo[1,5-a]pyrimidine-based compounds of the formula: are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by adaptor associated kinase 1 activity are also disclosed.
Public/Granted literature
- US20150183792A1 PYRAZOLO[1,5-a]PYRIMIDINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE Public/Granted day:2015-07-02
Information query
