Invention Grant
US09403838B2 Process for reducing contaminating Michael acceptor levels in oxycodone and other compositions
有权
用于减少羟考酮和其他组合物中污染的Michael受体水平的方法
- Patent Title: Process for reducing contaminating Michael acceptor levels in oxycodone and other compositions
- Patent Title (中): 用于减少羟考酮和其他组合物中污染的Michael受体水平的方法
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Application No.: US14586239Application Date: 2014-12-30
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Publication No.: US09403838B2Publication Date: 2016-08-02
- Inventor: Jules A. Shafer , Vladislav V. Telyatnikov , Hao Wang
- Applicant: Controlled Chemicals, Inc.
- Applicant Address: US PA Colmar
- Assignee: Controlled Chemicals, Inc.
- Current Assignee: Controlled Chemicals, Inc.
- Current Assignee Address: US PA Colmar
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A01N43/42
- IPC: A01N43/42 ; C07D489/08 ; C07D489/02
Abstract:
The present invention relates to processes for removal of Michael acceptors from certain compositions wherein the composition is treated with a thiol-containing compound under conditions sufficient to remove Michael acceptors and the resulting thiol-Michael adducts. Certain embodiments of the present invention enable quantification and/or removal of Michael acceptors and/or Michael acceptor precursors.
Public/Granted literature
- US20150148537A1 PROCESS FOR REDUCING CONTAMINATING MICHAEL ACCEPTOR LEVELS IN OXYCODONE AND OTHER COMPOSITIONS Public/Granted day:2015-05-28
Information query
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