Invention Grant
- Patent Title: Cysteine protease inhibitors and uses thereof
- Patent Title (中): 半胱氨酸蛋白酶抑制剂及其用途
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Application No.: US14376361Application Date: 2013-02-01
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Publication No.: US09403843B2Publication Date: 2016-08-02
- Inventor: Gregory R. J. Thatcher , Isaac Thomas Schiefer , Ottavio Arancio , Mauro Fa
- Applicant: The Trustees of Columbia University in the City of New York
- Applicant Address: US NY New York US IL Urbana
- Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Current Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK,THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Current Assignee Address: US NY New York US IL Urbana
- Agent Gregory P. Einhorn; Colleen A. Superko; Gregory Hook
- International Application: PCT/US2013/024364 WO 20130201
- International Announcement: WO2013/116663 WO 20130808
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D409/12 ; C07D417/12 ; C07D417/14 ; C07D303/48 ; C07D495/04 ; C07D405/12
Abstract:
The invention provides for novel cysteine protease inhibitors and compositions comprising novel cysteine protease derivatives. The invention further provides for methods for treatment of neurodegenerative diseases comprising administration novel cysteine protease inhibitors or compositions comprising novel cysteine protease inhibitors. In some embodiments, the cysteine protease inhibitors are calpain inhibitors.
Public/Granted literature
- US20150045393A1 Novel Cysteine Protease Inhibitors and Uses Thereof Public/Granted day:2015-02-12
Information query
