Invention Grant
- Patent Title: Acceptor framework for CDR grafting
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Application No.: US14706484Application Date: 2015-05-07
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Publication No.: US09403903B2Publication Date: 2016-08-02
- Inventor: Dominik Escher
- Applicant: ESBATech—a Novartis Company LLC
- Applicant Address: US TX Fort Worth
- Assignee: ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT LLC
- Current Assignee: ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT LLC
- Current Assignee Address: US TX Fort Worth
- Agent Jason J. Derry
- Main IPC: C07H21/00
- IPC: C07H21/00 ; C07K16/18 ; C07K16/46
Abstract:
The present invention relates to an antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a particularly well suited antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications.
Public/Granted literature
- US20150315294A1 ACCEPTOR FRAMEWORK FOR CDR GRAFTING Public/Granted day:2015-11-05
Information query
