Invention Grant
US09403906B2 Method of treatment of a solid tumor with interleukin-1 accessory protein antibody
有权
用白细胞介素-1辅助蛋白抗体治疗实体瘤的方法
- Patent Title: Method of treatment of a solid tumor with interleukin-1 accessory protein antibody
- Patent Title (中): 用白细胞介素-1辅助蛋白抗体治疗实体瘤的方法
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Application No.: US13979475Application Date: 2012-01-19
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Publication No.: US09403906B2Publication Date: 2016-08-02
- Inventor: Thoas Fioretos , Marcus Jaras
- Applicant: Thoas Fioretos , Marcus Jaras
- Applicant Address: SE Lund
- Assignee: Cantargia AB
- Current Assignee: Cantargia AB
- Current Assignee Address: SE Lund
- Agency: JL Salazar Law Firm
- Agent David L. Fox
- International Application: PCT/GB2012/050120 WO 20120119
- International Announcement: WO2012/098407 WO 20120726
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/30 ; A61K47/48 ; A61K51/10 ; C12N15/115 ; A61K39/00
Abstract:
The present invention provides agents comprising or consisting of a binding moiety with specificity for interleukin-1 receptor accessory protein (IL1RAP) for use in inducing cell death and/or inhibiting the growth and/or proliferation of cells associated with a solid tumour, wherein the cells express IL1RAP. A related aspect of the invention provides agents comprising or consisting of a binding moiety with specificity for interleukin-1 receptor accessory protein (IL1RAP) for use in detecting pathological cells associated with a solid tumor, wherein the cells express IL1RAP. Further provided are pharmacological compositions comprising the agents of the invention and methods of using the same.
Public/Granted literature
- US20140017167A1 Anti-IL1RAP Antibodies and Their Use for Treating Human Public/Granted day:2014-01-16
Information query
