Invention Grant
- Patent Title: Ketoreductase-mediated stereoselective route to alpha chloroalcohols
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Application No.: US15046011Application Date: 2016-02-17
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Publication No.: US09404092B2Publication Date: 2016-08-02
- Inventor: Yong Koy Bong , Michael Vogel , Steven J. Collier , Vesna Mitchell , Jagadeesh Mavinahalli
- Applicant: CODEXIS, INC.
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- Main IPC: C12N9/04
- IPC: C12N9/04 ; C12N15/53
Abstract:
The present disclosure relates to engineered ketoreductase polypeptides and uses thereof for the preparation of α-chloroalcohols from α-chloroketones. Also provided are polynucleotides encoding the engineered ketoreductase polypeptides and host cells capable of expressing the engineered ketoreductase polypeptides.
Public/Granted literature
- US20160160187A1 KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS Public/Granted day:2016-06-09
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