Invention Grant
- Patent Title: Antisense modulation of GCGR expression
- Patent Title (中): GCGR表达的反义调制
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Application No.: US14484638Application Date: 2014-09-12
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Publication No.: US09404114B2Publication Date: 2016-08-02
- Inventor: Susan M. Freier , Sanjay Bhanot
- Applicant: Ionis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Knobbe, Martens, Olson & Bear LLP
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/70 ; C12N15/113 ; C12Q1/68 ; A61K31/711

Abstract:
Provided herein are methods, compounds, and compositions for reducing expression of GCGR mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate metabolic disease, for example, diabetes, or a symptom thereof.
Public/Granted literature
- US20150099792A1 ANTISENSE MODULATION OF GCGR EXPRESSION Public/Granted day:2015-04-09
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