Invention Grant
US09404923B2 Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates
有权
用于检测非人灵长类动物感染或免疫的结核分枝杆菌特异性肽
- Patent Title: Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates
- Patent Title (中): 用于检测非人灵长类动物感染或免疫的结核分枝杆菌特异性肽
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Application No.: US14373286Application Date: 2013-02-07
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Publication No.: US09404923B2Publication Date: 2016-08-02
- Inventor: Kimberly Luke
- Applicant: INTUITIVE BIOSCIENCES, INC.
- Applicant Address: US WI Madison
- Assignee: INTUITIVE BIOSCIENCES, INC.
- Current Assignee: INTUITIVE BIOSCIENCES, INC.
- Current Assignee Address: US WI Madison
- Agency: Casimir Jones, S.C.
- International Application: PCT/US2013/025072 WO 20130207
- International Announcement: WO2013/119763 WO 20130815
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/554 ; G01N33/569 ; G01N33/543
Abstract:
The present invention relates to novel peptides that may be used in whole or in combination for the detection of Mycobacterium tuberculosis infection. In particular, the present invention relates to compositions and methods involving detection of antibodies contained in the blood of non-human primates that arise from an infection from M. tuberculosis or vaccination using an epitope specific inoculation. More particularly, the present invention provides a means to distinguish early, active, and latent M. tuberculosis infection. More particularly, the present invention describes an immunological diagnostic mechanism for the detection of M. tuberculosis infection.
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