The present invention provides an active radio frequency identification (RFID) tag and a system and method thereof. The system includes: a coordinator, configured to uninterruptedly and repeatedly transmit a wakeup instruction on a first channel, and a reader/writer, connected to a control processor, and configured to establish communication with the active RFID tag on a second channel after the active RFID tag receives the wakeup instruction, and transmit an action instruction index to the active RFID tag; wherein the active RFID tag comprises: a receiver, configured to receive the wakeup instruction during a time period of an interception state and receive the action instruction index; a processor, configured to store a preset index-action mapping relationship, be waked up according to the wakeup instruction and search out an action instruction corresponding to the action instruction index from the index-action mapping relationship, and execute an operation in response to the action instruction.