In a method of ensuring crop treatment compatibility crop treatment information is received at a computer system. The crop treatment information comprises a real-time location of a crop treatment applicator and a description of a crop treatment resident in the crop treatment applicator. Planted crop treatment information is accessed for a planted field which encompasses the real-time location. The planted crop information comprises a description of a planted crop in the planted field. It is determined whether the crop treatment is compatible with application to the planted crop. In response to determining the crop treatment is not compatible with application to the planted crop, a crop treatment incompatibility action is initiated in real-time from the computer system.