A system for serial comparison of physiological data, including: a controller; a user interface; and a memory including instructions that, when executed by the controller, perform the steps of: receiving from a first data source a current clinical report including first set of physiological data of a patient and computer-generated first interpretive statements; accessing, from the patient file in a patient database, a previous clinical report including a second set of physiological data of the patient and physician-edited interpretive statements; mapping the physician-edited interpretive statements into one or more codes of a structured data format, wherein each code uniquely identifies a medical state; performing a serial comparison between the current clinical report and the previous clinical report to generate serial comparison interpretive statements; providing to a user, via the user interface, the serial comparison interpretive statements; and receiving, via the user interface, current physician-edited interpretive statements.