Invention Grant
- Patent Title: Pharmaceutical composition for oral administration
- Patent Title (中): 用于口服给药的药物组合物
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Application No.: US14779328Application Date: 2014-03-28
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Publication No.: US09408835B2Publication Date: 2016-08-09
- Inventor: Seiji Takae , Hiroyuki Kojima , Atsushi Sakurai , Tetsuya Tamura , Hiroaki Tasaki , Atsushi Muro
- Applicant: ASTELLAS PHARMA INC.
- Applicant Address: JP Tokyo
- Assignee: ASTELLAS PHARMA INC.
- Current Assignee: ASTELLAS PHARMA INC.
- Current Assignee Address: JP Tokyo
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: JP2013-071361 20130329
- International Application: PCT/JP2014/059078 WO 20140328
- International Announcement: WO2014/157603 WO 20141002
- Main IPC: A61K31/437
- IPC: A61K31/437 ; A61K9/20 ; A61K9/28

Abstract:
A pharmaceutical composition containing, as the active ingredient, 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, of which the solubility in an acidic pH region is different from that in a neutral pH region, with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance, is provided. The pharmaceutical composition for oral administration of the present invention contains 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide or a pharmaceutically acceptable salt thereof, and a hydrophilic lubricant, and is useful as a pharmaceutical composition for oral administration with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance.
Public/Granted literature
- US20160045479A1 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION Public/Granted day:2016-02-18
Information query
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