Invention Grant
- Patent Title: Crystal entecavir, crystal entecavir formulation and methods for the preparation thereof
- Patent Title (中): 晶体恩替卡韦，晶体恩替卡韦配方及其制备方法
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Application No.: US14246029Application Date: 2014-04-04
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Publication No.: US09408849B2Publication Date: 2016-08-09
- Inventor: Deping Yi , Zhike Tian , Weidong Ye
- Applicant: Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
- Applicant Address: CN Huancheng Donglu
- Assignee: Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
- Current Assignee: Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
- Current Assignee Address: CN Huancheng Donglu
- Agency: McNeely Hare & War, LLP
- Agent William D. Hare
- Priority: CN200710004988 20070214; CN200710143096 20070823
- Main IPC: A61K31/522
- IPC: A61K31/522 ; A61K9/20 ; A61K9/48 ; C07D473/18
Abstract:
The present invention relates to a pharmaceutical composition for treating hepatitis B virus infection comprising crystalline entecavir as the pharmaceutically active ingredient and one or more pharmaceutically acceptable excipients. The tablet and capsule of the pharmaceutical composition have improved stability compared to that of amorphous entecavir under the conditions of light, high temperature and high humidity.
Public/Granted literature
- US20140220120A1 CRYSTAL ENTECAVIR, CRYSTAL ENTECAVIR FORMULATION AND METHODS FOR THE PREPARATION THEREOF Public/Granted day:2014-08-07
Information query
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