Invention Grant
- Patent Title: Substituted indazole derivatives active as kinase inhibitors
- Patent Title (中): 作为激酶抑制剂活性的取代的吲唑衍生物
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Application No.: US14116512Application Date: 2012-05-07
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Publication No.: US09408850B2Publication Date: 2016-08-09
- Inventor: Andrea Lombardi Borgia , Marina Ciomei , Daniele Donati , Marcella Nesi
- Applicant: Andrea Lombardi Borgia , Marina Ciomei , Daniele Donati , Marcella Nesi
- Applicant Address: IT Nerviano (MI)
- Assignee: NERVIANO MEDICAL SCIENCES S.R.L.
- Current Assignee: NERVIANO MEDICAL SCIENCES S.R.L.
- Current Assignee Address: IT Nerviano (MI)
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: EP11165882 20110512
- International Application: PCT/EP2012/058389 WO 20120507
- International Announcement: WO2012/152763 WO 20121115
- Main IPC: C07D231/56
- IPC: C07D231/56 ; C07D401/12 ; C07D295/185 ; C07D405/12 ; C07D403/12 ; A61K31/496 ; A61K31/416 ; A61K31/5377 ; C07D401/14 ; C07D403/14 ; A61K31/454 ; A61K45/06 ; C07D295/155

Abstract:
The present invention relates to substituted indazole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by degulated protein kinase activity, like cancer. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.
Public/Granted literature
- US20140080807A1 SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS Public/Granted day:2014-03-20
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