Invention Grant
US09408904B2 Scalable manufacturing platform for viral vector purification and viral vectors so purified for use in gene therapy
有权
用于病毒载体纯化的可扩展制造平台和如此纯化用于基因治疗的病毒载体
- Patent Title: Scalable manufacturing platform for viral vector purification and viral vectors so purified for use in gene therapy
- Patent Title (中): 用于病毒载体纯化的可扩展制造平台和如此纯化用于基因治疗的病毒载体
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Application No.: US13561753Application Date: 2012-07-30
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Publication No.: US09408904B2Publication Date: 2016-08-09
- Inventor: John Fraser Wright , Guang Qu , Bernd Hauck , Katherine A. High
- Applicant: John Fraser Wright , Guang Qu , Bernd Hauck , Katherine A. High
- Applicant Address: US PA Philadelphia
- Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
- Current Assignee: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
- Current Assignee Address: US PA Philadelphia
- Agency: Pillsbury Winthrop Shaw Pittman LLP
- Main IPC: C07K14/005
- IPC: C07K14/005 ; A61K39/235 ; C07K14/015 ; C12N15/35 ; C12N15/864 ; A61K39/23 ; A61K48/00 ; C12N7/00 ; C12N15/86 ; C07K2/00 ; C12N15/64
Abstract:
Methods for preparing highly purified AAV vector formulations are provided. The highly pure AAV formulations described herein are superior for clinical use.
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