Invention Grant
US09408926B2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
有权
KDR和VEGF / KDR结合肽及其在诊断和治疗中的应用
- Patent Title: KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
- Patent Title (中): KDR和VEGF / KDR结合肽及其在诊断和治疗中的应用
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Application No.: US14085645Application Date: 2013-11-20
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Publication No.: US09408926B2Publication Date: 2016-08-09
- Inventor: Christophe Arbogast , Philippe Bussat , Hong (Helen) Fan , Sudha Khurana , Karen E. Linder , Edmund R. Marinelli , Palaniappa Nanjappan , Adrian D. Nunn , Radhakrishna K. Pillai , Sibylle Pochon , Kondareddiar Ramalingam , Ajay Shrivastava , Bo Song , Rolf E. Swenson , Mathew A. Von Wronski , Feng Yan
- Applicant: Bracco Suisse S.A.
- Applicant Address: CH Manno
- Assignee: Bracco Suisse S.A.
- Current Assignee: Bracco Suisse S.A.
- Current Assignee Address: CH Manno
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Main IPC: C07K14/00
- IPC: C07K14/00 ; A61K49/22 ; A61K51/08 ; C07K7/08 ; C07K14/52 ; C07K14/71 ; A61K38/00
Abstract:
The present invention provides polypeptides, peptide dimers, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD
Public/Granted literature
- US20140161732A1 KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY Public/Granted day:2014-06-12
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