Invention Grant
US09408934B2 Compositions and methods for improving toughness of irradiated sterilized bone allografts
有权
用于提高辐射灭菌骨同种异体移植物韧性的组合物和方法
- Patent Title: Compositions and methods for improving toughness of irradiated sterilized bone allografts
- Patent Title (中): 用于提高辐射灭菌骨同种异体移植物韧性的组合物和方法
-
Application No.: US14055365Application Date: 2013-10-16
-
Publication No.: US09408934B2Publication Date: 2016-08-09
- Inventor: Thomas Willett
- Applicant: Sinai Health System
- Applicant Address: CA Toronto
- Assignee: Sinai Health System
- Current Assignee: Sinai Health System
- Current Assignee Address: CA Toronto
- Agency: Howson & Howson LLP
- Main IPC: A61L2/00
- IPC: A61L2/00 ; A61L9/00
Abstract:
The present invention relates to compositions, methods, kits and systems employing irradiation activated agents to improve or increase or prevent loss of toughness, work-to-fracture, post-yield toughness, fracture toughness and/or fatigue strength of a bone allograft on exposure to radiation. The irradiation activated agent can be an agent that increases crosslinking of collagen in bone during irradiation, for example ribose, 2-hydroxytetrahydropyran or ascorbate.
Public/Granted literature
- US20140112825A1 Compositions and Methods for Improving Toughness of Irradiated Sterilized Bone Allografts Public/Granted day:2014-04-24
Information query
IPC分类:
