A resilient seal for mobile living quarters around a slide out room that includes a pair of mounting portions extending along the inside and outside surfaces of the main living area wall at an aperture through which the slide out room moves and further includes a connecting member extending between the attaching members and along the edge of the wall defining the aperture. The seal includes a flexible protrusion that can conform to an irregular surface or for accommodating walls of different thicknesses. A wiper seal extends from the connecting member to flex against the walls of the slide out room.