Invention Grant
- Patent Title: Selective histone deactylase 6 inhibitors
- Patent Title (中): 选择性组蛋白去甲酶6抑制剂
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Application No.: US14383418Application Date: 2013-03-07
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Publication No.: US09409858B2Publication Date: 2016-08-09
- Inventor: Eduardo M. Sotomayor , Joel Bergman , Alan Kozikowski , Karrune Veeraprasert Woan , Alejandro V. Villagra
- Applicant: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. , BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
- Applicant Address: US FL Tampa US IL Urbana
- Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.,Board of Trustees of the University of Illinois
- Current Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.,Board of Trustees of the University of Illinois
- Current Assignee Address: US FL Tampa US IL Urbana
- Agency: Meunier Carlin & Curfman LLC
- International Application: PCT/US2013/029521 WO 20130307
- International Announcement: WO2013/134467 WO 20130912
- Main IPC: C07C275/28
- IPC: C07C275/28 ; A61K31/505 ; A61K31/44 ; A61K31/4045 ; A61K31/167 ; C07D239/42 ; C07D213/75 ; C07D209/14 ; C07C275/34 ; A61K45/06 ; A61K31/422 ; A61K31/437 ; A61K31/454 ; A61K31/69 ; A61K38/00
Abstract:
Disclosed are selective histone deactylase inhibitors (HDACi) that having Formula (I). Methods of making and using these inhibitors for the treatment of cancer, in particular melanoma are also disclosed.
Public/Granted literature
- US20150056213A1 SELECTIVE HISTONE DEACTYLASE 6 INHIBITORS Public/Granted day:2015-02-26
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