Invention Grant
- Patent Title: Crystal modifications of elobixibat
- Patent Title (中): elobixibat的水晶修饰
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Application No.: US14920080Application Date: 2015-10-22
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Publication No.: US09409875B2Publication Date: 2016-08-09
- Inventor: Martin Bohlin , Erica Tjerneld , Andreas Vestermark , Ingvar Ymen
- Applicant: Elobix AB
- Applicant Address: SE Gothenburg
- Assignee: Elobix AB
- Current Assignee: Elobix AB
- Current Assignee Address: SE Gothenburg
- Agency: Fish & Richardson P.C.
- Priority: SE1350517 20130426
- Main IPC: C07D281/10
- IPC: C07D281/10 ; C07D281/02
Abstract:
The present invention relates to crystal modifications of N-{(2R)-2-[({[3,3-dibutyl-7-(methyl-thio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-8-yl]oxy}acetyl)amino]-2-phenylethanolyl}glycine (elobixibat), more specifically crystal modifications I, IV, MeOH-1, EtOH-1, 1-PrOH-1 and 2-PrOH-1. The invention also relates to a process for the preparation of these crystal modifications and to a pharmaceutical composition comprising crystal modification IV.
Public/Granted literature
- US20160039777A1 CRYSTAL MODIFICATIONS OF ELOBIXIBAT Public/Granted day:2016-02-11
Information query
